XRDML is a filename extension associated with a program for analyzing diffraction in crystals, developed by PANalyticial.

XRDML files are used for storing analytical data collected by external measuring devices. XRDML files store data in XML format. Originally XRDML were binary files, but due to various difficulties with parsing binary data for information the specification was changed to text format. X-ray diffraction is a process of determining chemical composition and crystalline structure of materials.