File with a .MANIFEST filename extension contains data in XML format, specific for Windows OS applications, like MANIFEST or package content, used during configuration and implementation of application in Microsoft Windows - ClickOnce and Common Language Runtime CLR technology. It is used mainly by programmers, filename extension is often compiled with the .EXE.MANIFEST executive file name.

MANIFEST files are usually hidden for users, however, if they are noticed in the installation directory, it is advised not to modify their content, as it may disturb functioning of the software. In order to achieve software’s faster access to the parameters of a given application contained within the MANIFEST files, they are often compiled to files with the .CDF-MS filename extension, which can be found along these files in the application’s directory.